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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

不要误以为最后时刻的风平浪静就意味着截止期限前的动作是平淡无奇的:
英国门萨首席执行官约翰·斯蒂门尼奇说他为妮诗感到高兴。他说:“我希望她能充分利用好成为门萨会员的机会,结交志趣相投的新朋友,不断挑战自己。加入门萨,就为你打开了一扇大门。门萨是一个会员超过10万人的世界网络,很多会员会成为终生好友。”

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Bobbi's dad Anton, 28, admits that he had his concerns at first, but is now comfortable with Bobbi's routine.
bene好,fit做-做事后的好处

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

萝丝王

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

据当地媒体报道,这一犯罪团伙设在广西壮族自治区首府南宁,他们向腐肉中注射化学药品,使其增重50%,这样每吨腐肉便可获利16000元人民币(合1750英镑)。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

[.h?spi't?liti]
对于精打细算的旅客来说,尼泊尔一直是绝佳的好去处。无论是该地区的徒步路线还是南部地区的野外生物,在世界范围内都是赫赫有名。平均每人每天的旅行花费大概只在50美元左右。
Take the intriguing reintroduction of “unfeigned regards” — last big in the 18th century and now found on emails from Indian help centres. But the winning sign-off, at the bottom of a message sent one Friday, was: “weekend well”. I nearly awarded it second prize for the best noun pretending to be a verb, though at the last minute this award was snatched by a consultant overheard saying: “Can we cold towel that?”
Although the timing is purely a coincidence, it can’t hurt that Magento’s first product manager, Tim Schulz, just joined Bigcommerce as senior vice president of product management. Most recently a strategic partnership and business development executive for Google for services such as Shopping Express and Wallet, Schulz will be sharply focused on ensuring Bigcommerce offers an integrated experience that better straddles the e-commerce and physical retail worlds. “Consumers just want a seamless experience,” he said.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 中秋小长假楼市告别“金九”
Perspective

Trends and targets in antiviral phototherapy

rough
Belgium and Uruguay are two diminutive countries that have maximized their advantages through inclusiveness, and of which Brazil, Argentina, Spain and Germany -- the quartet of forerunners for this year's title -- will rightly be wary. They, in the manner of Brazil's indigenous mosquitos and scorpions, are a useful reminder that small can often be deadly.
通过ETF购买计划,日本央行间接持有约22家日本大企业10%的股权,并持有整个日本股市的3%左右。一些人批评称,这是对日本股市“事实上的国有化”。
[k?n'tinju?s]

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

你肯定知道,那个似乎永远都待在公司的老家伙现在依然不会使用电子邮件。到了2014年,如果你跟不上社交媒体的新潮流,你就跟那个老家伙没什么两样。今年发布于招聘信息搜索引擎Indeed.com的招聘广告,提及社交媒体使用技能的是去年的13倍。Indeed公司传讯总监艾米?克劳今年初接受数字经济新闻网Quartz采访时说:“从人力资源到产品开发,再到客户服务,企业各个部门对精通社交媒体的求职者的需求正在急剧增加。”预计将出现在Twitter和Facebook上的不仅仅是市场、销售和客服等部门,研发、物流和人力资源等差异巨大的团队也越来越多地使用Yammer等内部网络以简化操作流程。事实上,社交媒体已经发展为职场技能的重要一环,就连各大高校现在也纷纷面向不善社交的企业开设认证项目,帮助它们适应日新月异的社交媒体世界。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 家纺行业挤泡沫 企业扩张放缓
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Airlines with operations based west of the Rockies boast the fewest flights that arrive late during the holidays, according to data compiled for Forbes.com by FlightAware.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Comparing regions within specific categories of costs, the EIU notes that Asian cities are the most expensive for grocery shopping, with Seoul in South Korea the priciest for food. European cities are the most expensive in terms of recreation and entertainment.
排名:第一

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

D'ALOISIO HAS BEEN quoted opining that 'time is the new currency.' It's the driving notion behind Summly. It's also a strangely wise observation from a 17-year-old. At that age, many of us had more time on our hands than we knew how to fill without plummeting into severe boredom. It's easy to forget-conversing over lunch in a London caf钼 or strolling through the Tate Modern-that D'Aloisio was born in 1995 and has not yet graduated from high school. Or that he still lives in his childhood bedroom, in a cozy upper-middle-class home. As I chat with his parents, he excuses himself to work on his computer. Slouching down the hall in his stocking feet, hems of his skinny jeans brushing the hallway carpet, it is the most kidlike you will ever see him.
“有1400人出境去参加圣战,加入叙利亚和伊拉克境内的恐怖主义组织。” Valls告诉BFMTV。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
From the themed collection: 宜家家居成三月份曝光率最高卖场
Open Access Review Article

Diagnostic technologies for COVID-19: a review

网络红人前10名的微博粉丝数加起来超过了4000万。其中最著名的Papi酱签署的视频广告价值竟然达到了令人震惊的2200万元。
涨幅放慢也与房地产投资变化趋势吻合。上月,一二线城市的限购措施对房地产投资造成了(些许)冲击,全国范围内的房产成交量和成交金额的增速也有所减缓。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

Such claims are unlikely to go away, though. John R. Christy, an atmospheric scientist at the University of Alabama in Huntsville who is known for his skepticism about the seriousness of global warming, pointed out in an interview that 2014 had surpassed the other record-warm years by only a few hundredths of a degree, well within the error margin of global temperature measurements. “Since the end of the 20th century, the temperature hasn’t done much,” Dr. Christy said. “It’s on this kind of warmish plateau.”
《敦刻尔克》
The banking industry has been experiencing a low profit growth period and will be for a long time, the National Business Daily reported, citing an expert. He said the banks' yearly profits growth reached 35 to 40 per cent in the past dozen years, but now the growth had slowed to less than 1 per cent, with some banks even recording a loss.
推进农业结构调整。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

当时的杜兰特身高6尺9寸,体重只有185磅,我很惊讶在高中赛打到一半时他没有被撞坏。幸运的是,杜兰特不靠在大前锋位置上力量抗衡赚钱,他主要依赖他拿手的急停跳投。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

判断权在你手里。
故事背景设定于《星球大战3:西斯的复仇》和《星球大战4:新希望》之间,起义军盗取死星设计图,将很有可能成为被重金追杀的对象。对于电影详细情节,我们也不是很清楚。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

在007电影主题曲榜单上,《女王密使》的主题曲获得荣誉推荐。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
From the themed collection: 迎接2.0时代绿建行业整装待发
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

When scientists discover how to shrink humans to five inches tall as a solution to overpopulation, Paul (Matt Damon) and his wife Audrey (Kristen Wiig) decide to abandon their stressed lives in order to get small and move to a new downsized community, a choice that triggers life-changing adventures.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Are you often irritable?
The U.S. Veterans Day holiday also coincides with other World War One-era holidays around the world, including Remembrance Day in Britain and the Commonwealth nations of Australia and Canada.
去年我国内地人口总数达13.7亿,与2010年进行人口普查时相比,人口数量增加了3377万,这意味着人口年增长率为0.5%。
《善地》

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

the Dutch lender that is a leading financier to farmers and agribusinesses around the world.
目前正在调查最佳影片奖是如何被错误地念成《爱乐之城》而非真正得主《月光男孩》的。
在本周达沃斯年会上,政策制定者、政治人士以及商业领袖达成了这种谨慎乐观的共识,这种局面是自2007年以来历届世界经济论坛所不曾看到的。
adj. 复杂的,复合的,合成的
Banking

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

At Japan Expo, we are very honored to interview Gen Urobuchi and also begraced with the presence of Nitro+ president Takaki Kosaka.Let's begin.Translated by Emmanuel Bochew.
The clip, taken on a mobile phone, starts with the crowd singing the Frankie Valli lyrics: You're just too good to be true, can't take my eyes off of you'.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

8.Please aid the Olympic authorities and organisers by demonstrating at all times that you are not a terrorist. Do not perspire, take off your shoes, smile in a weird way while texting someone, or point and shout: "Hey! Look at all those missiles on that roof over there!" In fact, if you're not using your hands for anything, it's probably best if you keep them in the air where everybody can see them.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Foreigners with permanent residence enjoy the same rights as Chinese citizens, such as in investment, housing purchases and schooling, among other rights.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Social scientists, after crunching data from both sides of the Atlantic, have discovered something surprising: it’s not the amount of racial or ethnic diversity in a community that predicts white resentment and support of anti-immigrant policies, but the pace of change.
今年登榜的还有“starwars”(星球大战),排名第16。
一位著名神经学家的遗作引发的争议
However, the state is also wary of the fast growth in online finance, which is largely unregulated and the risks of systemic crises may be high. Since 2007, 370 P2P lending platforms have failed in China, of which 270 failed in the past year, according to research by Morgan Stanley and Wangdaizhijia, a Chinese research group.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

EMBAGlobal is the only programme in the top 10 that saw a slight drop in the average salary of its alumni compared with last year (the other nine recorded strong increases).
Wages will finally accelerate after years of stagnation
Mila Kunis just keeps on raking in those sexy titles.
●Van Full Of Illegals Shows Up To Vote Clinton At SIX Polling Places, Still Think Voter Fraud Is A Myth?

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

Next year, the mayor’s affordable housing plan, which calls for building or preserving 200,000 units of affordable housing over the next decade, will begin to take shape. It hinges on a policy that requires developers to build affordable housing in exchange for being allowed to construct taller and denser buildings in neighborhoods rezoned by the city. Developers and housing advocates alike are waiting to see what it will look like once the administration adds muscle and flesh to the bones of the proposal.
德国总理默克尔的年收入为21.84万欧元(约合24.2万美元)。德国总理的薪水在今年三月初上调2%,并将于明年二月继续上调2%。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Deadpool will release on February 12, 2016 and it looks like it's going to be a hilarious movie. Oh yes, there's going to be plenty of action and killing as well.
8. 随着养老金抽干州市财政,就业前景疲弱
第十步 如果以上几条都做不到——就公告天下说你有反社会人格
新加坡已经连续三次被列为世界上生活成本最贵的城市,但是这一年中城市生活成本在世界范围内的分布有了显著的变化。
【英文原文】

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

冲击奖项:最佳电影提名应该可以肯定。参演《至暗时刻》的加里奥德曼是最佳男主角的最热人选,如果说有谁能击败他的话,那可能就是克莱门特了。
这里有一些散步和骑行的小径可通往其他的湖滨社区以及市中心,骑车去市中心15分钟可达,开车10分钟。附近有步行者艺术中心(Walker Art Center)和几座博物馆。冬天湖上很多人玩冰球和滑冰运动;夏天则流行划独木舟、游泳和钓鱼。
对于那些已把自家公寓改造成B&B旅店的纽约人,围绕非法住宿的论战可能会趋于白热化。而在这一切之上,市长比尔·白思豪(Bill de Blasio)的十年保障性住房计划将初具规模;与此同时,本次奥尔巴尼会议(Albany)的立法将给租房者的钱包造成重负。随着我们迈向新的一年,这类改变游戏规则的因素也正在日益迫近。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

7.管理多向性
城镇新增就业1100万人以上,城镇登记失业率4.5%以内;

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 绿色建材发展即将驶入“快车道”
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 谷歌智能家居内乱启示录
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

The 54-episode series The Journey of Flower was one of the hottest topics on social media. The TV drama became a hit in the summer of 2015. The movie starring Huo Jianhua and Zhao Liying is based on a novel of the same title written by Fresh Guoguo. The aesthetical adaptation has picturesque outdoor scene in a Chinese ink painting style and charming male and female lead roles, attracting 800,000 followers on the drama`s official Weibo. The drama premiered in June of 2015. It tells a story from a female perspective of an orphan`s growth and romance on her way to becoming a goddess.
James Bond Themes 4. "Thunderball" by Tom Jones
Total program cost: $168,000

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Outbound investment for the period totalled $86.3bn, according to the Ministry of Commerce.
《固定电话》是今年唯一一部必看的家庭喜剧/剧情片。
而新上榜的中国公司则包括万科、中铁公司和中国太平保险。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

The consumer price index rose by 1.8 per cent year-on-year in January, from 1.6 per cent in December 2015. However, CPI continues to trail Beijing’s target of “around 3 per cent“.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

但与其他世界主要国家领导人相比,这薪酬已经是最高了。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

普京对俄罗斯经济做出积极评价。他说,经济已渡过危机,至少渡过了危机的高峰。
下面是开发一个商业平台时需要考虑的主要元素。这些元素可以帮助任何新公司制定明智的策略:

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Colliding Neutron Stars
A robust LinkedIn presence is crucial to any job search. You know that. Your manager knows that. And your manager probably knows that you know that – so she'll be concerned when you go from having a bare-bones profile on Monday to one jacked with additional work history, new connections, status updates and recommendations by Friday. "Don't go from zero to 500 overnight, because that can be quite obvious," Foss cautions。
格罗斯出尔反尔,不可理喻:四个月前他还警告说美联储正在构造一颗信贷超新星、一个新的信贷泡沫,这个泡沫将击垮贝南克资助华尔街庞氏骗局、吹起一个巨大金融泡沫、进而将美国之未来置于巨大风险之下的自负的、高风险的实验。
1=somewhat false

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

此器于2012年由考古学家发掘出土,此后一直保存在仪征博物馆,未向对外展示。
今年2月的时候,玛蒂与希雅和克里斯汀?韦格(Kristen Wiig)一起担任2015格莱美音乐颁奖典礼(Grammy Awards)的表演嘉宾。当时金?卡戴珊(Kim Kardashian)和坎耶?韦斯特(Kanye West)坐在前排观看了这个表演。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

当你在求职布告栏比如Monster或者Indeed发布你的简历时,你现在的雇主是可有机会看到你的简历的。Foss说很多人事和经理经常在求职栏搜索职工的名字看他们是不是在找工作。
Yet if “Mad Men” showed us anything (besides how cool a skinny suit could look, and that wide ties really were not a good men’s wear moment), it is that the decade chronicled was a complicated, often unhappy, occasionally destructive time.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
From the themed collection: 红木家具鉴定或引广州卖场效仿
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

她说早在去年12月份,她第一次看这部电影的时候,就注意到了自己和电影中的女主角长得十分相似,当时她觉得十分诡异。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

克里斯蒂亚诺·罗纳尔多,这位去年收入6100万英镑的超级足球明星,取代了长期占据榜首的弗洛伊德·梅威瑟,成为了去年收入最高的运动员。小梅瑟威是一名退役拳击手,他最近一年只打了一场拳赛,挣了3000万英镑。
最佳竞技真人秀:《美国之声》(The Voice , NBC)
Performances by Kelly Clarkson, Tim McGraw, Taylor Swift, Carrie Underwood and Miranda Lambert rocked the house at the MGM Grand Garden Arena.
Finally, in the EMBA ranking, excluding joint programmes delivered with non-European schools, IMD of Switzerland, with an average salary of $261,397, is well ahead of Business School in second and IE Business School in third place.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 上半年全国陶瓷出口数据公布
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

……太紧张,差点昏过去。
你要去里约看奥运会吗?你会在安卓或者iOS上装谷歌地图这个应用软件吗?我想你已经有了答案了。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

In early 2005, Stone and her co-founders Elisa Camahort Page and Jory Des Jardins noticed that there were countless women blogging, but mainstream media rarely linked to their posts. The trio decided to host a grassroots conference that year and attracted sponsors like Google and Yahoo. It quickly sold out and soon after, they launched BlogHer.com. The publishing platform turned blogging into a lucrative business for many women -- it paid $25 million to 5,000 of its bloggers between 2009 and 2012 -- and now reaches an audience of 92 million.
All-cash buyers. Skittish lenders. Skyrocketing prices. Anemic listings. These realities haunt buyers, turning the house hunt into a demoralizing slog. Unfortunately, buyers will probably have to soldier through another year of a market that favors sellers.
宾夕法尼亚州立大学的气候科学家迈克尔·E·曼恩(Michael E. Mann)在电子邮件中说,“如果不是由于燃烧化石燃料所产生的、导致地球变暖的气体排放越来越多的原因,在上千年史无前例的几十年较暖期间、创纪录地变暖的十年中,看到变暖的又一个记录年度,是非常不可能的。”

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

单词approval 联想记忆:
surrogate
1. Choosing a job based on compensation alone

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

['t?]
I experienced this pessimism personally in Davos in January 2014. Several leading western intellectuals asked me whether war would break out between China and Japan. I was so confident that there would be no war in east Asia that I offered to take bets with ten-to-one odds against myself with eminent western journalists. Two took up my bets. And I will be collecting on these bets when I return to Davos in January.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

1. Buy expensive tailored clothing that only sort of fits so that most of the time your buttons appear to be just seconds from bursting.
However, others argued that doctors' hands may be forced by an unfair system. "As a patient, I'm more concerned about whether they can cure my illness rather than how many papers they've published," another netizen said.
Man-made climate change is the main culprit for warming that was leading the world into “uncharted territory”, said Peter Stott, head of climate monitoring and attribution at the UK Met Office’s Hadley Centre for climate research, which released separate findings confirming the US analysis.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

v
游戏平台:Xbox One、Xbox 360、PS4、PS3 、PC

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

When you are at work, you are supposed to be productive. Otherwise, it's a waste of your time and the company's money. If you are bored and surfing the web most of your work day, you may want to think about looking into job options where you'll get more stimulation and responsibilities.
Australian and Spanish schools are doing well, however. Each country’s three representatives have risen up the ranking. Sydney’s Macquarie Graduate School of Management is Australia’s top placed institution at 49 and Spain’s IE Business School moved up four places to eighth, the first time since 2012 that the Madrid school is back in the top 10.
信任感依然会是商业领域中唯一且最关键的问题。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 海南部分湿地遭房地产开发蚕食
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

祝你享尽新年佳节的快乐和新年的礼品。

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Consumer prices rose 2.3 per cent year-on-year, more than expectations of 1.8 per cent. That is the biggest rise since July 2014. They had risen 1.8 per cent in January.
美国的麻省理工斯隆管理学院(MIT Sloan School of Management)位居第五,从而阻止了法国商学院囊括前五名。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 北京冬奥村赛后将变身人才公租房
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Benchmark oil prices dropped below $40 a barrel last week, the lowest level in six years, darkening investor sentiment towards commodity-linked companies and exporting countries including Brazil, Russia and South Africa.
随着PC端的消亡,再用病毒攻击他们就没那么有趣了。我认为恶意软件、蠕虫病毒和其他病毒都会很快入侵平板和手机。结果就是,我们要更卖力地保护自己的设备。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

当时,身为首席执行官的库克也承受着压力,因为苹果除了从iPhone攫取利润之外,缺乏清晰的产品开发方向。维权投资者嗅到了血腥,开始围攻这家公司,打头的是大卫?艾因霍恩(David Einhorn),接着是卡尔?伊坎(Carl Icahn),他们游说改变苹果的经营和财务管理方式。伊坎施压要求苹果筹集巨额债务,向股东返还1500亿美元,并敦促苹果发布包括电视机在内的更多产品。
encourage

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

spontaneous
Carry out deleveraging in an active and prudent way.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 去年全国300城土地收入破4万亿
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

em进入,brace胳膊-拥抱

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Jude Webber
My hunch is that this draft will look pretty good by March and will be much better than last year's, which was one of the most underwhelming in recent memory. New Orleans and Washington both need some direction, and soon.
希拉里?克林顿和唐纳德?特朗普之中的一人有望于在十一月的美国总统大选中胜出,就任年薪40万美元的总统一职。
2. 2012年搞笑诺贝尔奖之和平奖

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

vt. 忽视,疏忽,忽略

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

获奖者:布兰妮·斯皮尔斯
The number of people holding degrees from colleges or universities reached 170.93m, which means there were 12,445 people with an advanced education per 100,000 people in 2015, up from 8,930 in 2010. The number of people who had attended a senior high school also increased, and the number who had only completed lower-level education fell.
But we at The BostonConsulting Group believe that the current dip in China’s growth will not endureand that, under Xi’s leadership, China’s economy is destined to continuegrowing at a rapid clip. In fact, we are confident last week’s reforms willcontribute mightily to China’s growth between now and 2020. We stand by our base case forecast that China will deliver$4 trillion in growth over the next decade and combine with India to deliver a$10 trillion prize — an economic powerhouse driven by booming middle classconsumption and growing overall optimism. No one can perfectly forecastthe future … and in our book we describe scenarios where growthslows. But we remain optimistic and positive about China’s future.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

这是连续第二个周末,委内瑞拉的社会主义政府开放与哥伦比亚长期封闭的边界,星期日上午6点,潜在的顾客们排成长蛇阵,穿过圣安东尼奥德尔塔奇拉整个小镇。有些人租了车,从10小时车程外的城市赶来。
As the calendar flips to December it’s not too early to think about the inevitability of tanking. Who should do it, who should wait, and who shouldn’t ever consider it. Flanns and Zillz discuss.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

The Asia-Pacific region was the main driver of international growth at movie houses, up 13%, and China accounted for nearly half of the entire Asia-Pacific total.
马克斯将与她的朋友克洛伊一起,揭开她的同学雷切尔o安布尔神秘失踪背后的真相。游戏具有电影的体验感,配有不拘一格的原声,将当下年轻女孩的焦虑与生死攸关的情境结合了起来,再加上了时光倒流的能力,这一切使得这款游戏脱颖而出。尽管该作品中采用的机制在其他游戏中曾经用过,但由法国开发商制作的美国风格游戏,还是让这种定时操作有耳目一新的感觉。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

10. A bad marriage can lead to an early death

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 三大因素导致水泥行业产能过剩
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

China's 2016 office box sales are expected to exceed the 2015 total of 44 billion yuan (6.8 billion U.S. dollars), the country's film watchdog said.
QK%.jd&KnAkQ
absolutely

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 日本研发出高性能变色发光涂料
Paper

Length-scale dependence of protein hydration-shell density

“授课的是一流从业者,”该学院一名毕业生表示,“该项目为只有极少金融业工作经验的年轻专业人士量身打造,学生们毕业后马上就能投入工作。”
据新华社报道,2015年教育部和其他5个中央政府部门一起组成了一个专门工作组,以保障足球在中国学校里的蓬勃发展。
A fascinating study from researchers at the University of North Florida reveals that running barefoot may actually improve your memory more than running with shoes. While most memory studies seem to take place in a laboratory or room where everyone sits at a table, this experiment definitely introduced an interesting idea to the search for a better memory. The experiment focused on something called "working memory," which is the human ability to process information and recall details throughout life. The scientists published the results of their study in "Perceptual and Motor Skills," and found that running barefoot resulted in a not-insignificant memory boost when compared with memory performance after running with shoes. The researchers found that tossing your shoes off and running for about 16 minutes at a comfortable pace could result in a 16% improvement in working memory performance.
recept接受+ive表形容词→善于接受的

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

家用电器行业的平均价值上升了74%,是10大行业里上升幅度最大的。电子商务和零售业位居其后,价值上涨了69%。医疗卫生保健行业上升32%。金融服务行业上升了18%,酒类行业上升了17%。房地产增长了15%,饮食行业上升了11%。
Hayley Williams remains a powerful up-front presence, a belter who can croon as convincingly as she can yelp. Her vocal bravado almost makes you forget that After Laughter is an up-close chronicle of her weariness with the world.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

A lone European telephone bidder paid a top price of 9.1 million for a smaller 1825 version of John Constable’s admired but difficult-to-love 1824 vertical landscape, “The Lock,” that had been in the same British family since 1855.
关注规模较小和私营制造企业的财新制造业PMI下降,而主要关注规模较大和国有企业的官方制造业PMI指数同期出现上升。这种分歧可能表明,比起规模较大和国营的企业,较小的企业受污染限制和其他监管收紧的冲击更为严重。前者还享受国有银行的优惠待遇。
鉴于计算机编程被冠以“美国经济中尚未开垦的处女地”称号,纽约编程及设计学院正在努力让“谈论”代码变得更简单。到2020年,美国市场上将会有150万个计算机科学相关岗位,而计算机科学专业毕业生则仅有40万人。此外,计算机科学相关岗位在全美的平均增长率是其他职位的两倍。但是如果你并没有计算机科学专业学位,也没有计划重返校园又该如何呢?纽约编程及设计学院通过提供夜校课程和密集型研讨会的方式正在令学习网络设计和开发变得简单——从该项目毕业后,创建一家全新的网站,或是着手寻找技术相关的职位,并不是什么稀罕的事情。正如创始人杰瑞米?司乃帕(Jeremy Snepar)所言,在当下的数字化经济中,你不能不懂得怎样编程。他将编程看做是一种技术能力,一种能够也应该以更为简单的方式学习的能力,而纽约编程及设计学院正是为那些曾经感慨过“如果我懂怎样编程就好了”的人填补了一个重要的空白。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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But we are going to get a taste of the new world order when the WTO’s members gather for its biennial ministerial in Buenos Aires in December. It’s unclear, as always, if the WTO will be able to deliver anything of substance. But the real test lies in not having the US leading the way in discussions for the first time in the WTO’s life. Will China step in? The EU? And will India be as minded to block any deal as it has been in the past?
我们当中很多人都有八卦抱怨的习惯。但是如果做的太频繁的话,工作恐怕就不保了。所有的这些会带来一个同样的结果:变成了老板的眼中的麻烦。一般来讲,老板要确保自己的团队有正面的能量,团队中如果有人是消极的,会有损他的形象。消极的员工在高级管理层中被认为是“癌细胞”,这是因为“他们早晚会被割除”。如果你有怨念的话,一个好的办法就是私底下直接和老板对话。 千万不要一开始就拉拢人心寻求支持。

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